Based on a systematic assessment of changes in external circumstances and their impact on Beijing, this article analyzes the key issues faced by Beijing in several key areas during the 15th Five-Year Plan period, including economic growth, technological innovation, population structure, and the coordinated development of Beijing-Tianjin-Hebei region. The article proposes strategies to enhance the diversity of economic growth drivers, improve the agglomeration capacity of resources in the plain areas and their contribution to overall economic growth, establish innovation alliances led by technology-driven enterprises, shift from population size regulation to the adjustment of population structure and distribution, deepen the integration of innovation and industrial chains in the Beijing-Tianjin-Hebei region, and accelerate the development of new quality productive forces with the “Innovation Triangle” of Beijing-Tianjin-Xiong'an as the core.