Elevating the development capacity of the Chengdu-Chongqing Economic Circle represents a pivotal initiative in China’s high-quality territorial spatial planning. In alignment with the CPC Central Committee’s strategic blueprint for regional coordination, this analysis examines the strategic significance, key priorities, and policy measures for advancing the region’s development. The focus should be on enhancing five critical dimensions: optimizing resource allocation, strengthening internal-external circulation integration, driving innovation through source-driven mechanisms, facilitating green and low-carbon value conversion, and ensuring emergency backup security. Furthermore, it is essential to reinforce strategic guidance, infrastructure development, and major productivity layout support for the Chengdu-Chongqing Economic Circle.